I previously highlighted that mushrooms have an unique phytochemistry profile of biologically active compounds that provide us a lot of health benefits. (What Is The #1 Benefit Of Mushrooms)
These compounds inure the mushroom’s adaptations to survive in their relatively harsh habitat. They are mostly isolated from their root network called Mycelium which grows under the substrate whether soil or a tree’s trunk.
Let’s dive in some more on a few of these special compounds.
L-ERGOTHEONINE is a unique amino acid abundant in medicinal mushrooms. Ergotheonine is an antioxidant and serves as a cell protective function. It was found to be linked to reduced risk of cardiovascular disease and diabetes. In a long-term analysis of a population in Sweden, L-ergothioneine was identified as having a strong correlation between healthy eating habits and reduced cardiometabolic morbidities.
TERPENES are compounds that give plants and mushrooms their unique odor. Terpenes generally have specific roles in a mushroom's life, such as warding off predators and helping recover from injuries. Isolated terpenes from Chaga demonstrate ability to induce apoptosis (cell death) of specific cancer cells. Some can reduce inflammation and help manage allergies.
BETA-GLUCANS are a type of polysaccharides—branched chains of glucose units—that serve as a structural component of the cell walls of the mushroom’s fruiting body. They activate cells in the immune response and may be helpful to take when your immune system is challenged. Also many clinical studies are showing that Beta-glucans improve the desirable anti-tumor effects of some chemotherapies. Finally, Beta-glucans could lower cholesterol synthesis. Your gut bacteria can digest Beta-glucans and produce small chain fatty acids, which, in turn, inhibit a critical enzyme in the synthesis of cholesterol (called HMG-CoA).
CORDYCEPINS are primarily found in cordyceps mushrooms. They may literally have the same effect as exercise without breaking a sweat. Cordycepins are analogs or similar to a class of compounds called nucleosides, more specifically Adenosine. Adenosine also makes ATP (Adenosine Triphosphate)--the universal molecule that powers all of our cells and muscles with energy. Our cells are very sensitive to ratio of ATP versus AMP. Cordycepins drives that ratio down and turns on our cells to metabolize sugars and fats in order to make more ATP. In fact, cordyceps became popular as a performance enhancer.
Our mushrooms are sourced and grown in the USA. We use manufacturers in the US utilizing GMP conditions in their facilities. Every serving provides you 1000mg of extract from the mushroom’s mycelium. Plus, our mushrooms are standardized to 40% polysaccharides (400mg per serving). Go to our mushroom collections to explore more about how each of these mushrooms work.
Follow these scientific articles and learn about our understanding of the pharmacology of Mushrooms.
- Cerletti, C., Esposito, S., & Iacoviello, L. (2021). Edible Mushrooms and Beta-Glucans: Impact on Human Health. Nutrients, 13(7), 2195. https://doi.org/10.3390/nu13072195
- Sima, P., Vannucci, L., & Vetvicka, V. (2018). β-glucans and cholesterol (Review). International journal of molecular medicine, 41(4), 1799–1808. https://doi.org/10.3892/ijmm.2018.3411
- Smith, E., et al. (2020). Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease. Heart (British Cardiac Society), 106(9), 691–697. https://doi.org/10.1136/heartjnl-2019-315485
- Cheah, I. K., & Halliwell, B. (2021). Ergothioneine, recent developments. Redox biology, 42, 101868. https://doi.org/10.1016/j.redox.2021.101868
- Géry, A., et al. (2018). Chaga ( Inonotus obliquus), a Future Potential Medicinal Fungus in Oncology? A Chemical Study and a Comparison of the Cytotoxicity Against Human Lung Adenocarcinoma Cells (A549) and Human Bronchial Epithelial Cells (BEAS-2B). Integrative cancer therapies, 17(3), 832–843. https://doi.org/10.1177/1534735418757912